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Effect of different concentrations of desonide disodium phosphate (DES) on <t>prostaglandin</t> <t>E2</t> (PGE 2 ) accumulation in the aqueous humor at 24 h from the intravitreal injection of the lipopolysaccharide (LPS). Data are graphed as floating bars, spanning from minimum to maximum, and as a line at the mean value of measurements in 10 animals per group. ** p < 0.01, One-way ANOVA plus Holm–Sidak post hoc test, DES vs. saline (VHC).
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Effect of different concentrations of desonide disodium phosphate (DES) on <t>prostaglandin</t> <t>E2</t> (PGE 2 ) accumulation in the aqueous humor at 24 h from the intravitreal injection of the lipopolysaccharide (LPS). Data are graphed as floating bars, spanning from minimum to maximum, and as a line at the mean value of measurements in 10 animals per group. ** p < 0.01, One-way ANOVA plus Holm–Sidak post hoc test, DES vs. saline (VHC).
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Effect of different concentrations of desonide disodium phosphate (DES) on prostaglandin E2 (PGE 2 ) accumulation in the aqueous humor at 24 h from the intravitreal injection of the lipopolysaccharide (LPS). Data are graphed as floating bars, spanning from minimum to maximum, and as a line at the mean value of measurements in 10 animals per group. ** p < 0.01, One-way ANOVA plus Holm–Sidak post hoc test, DES vs. saline (VHC).

Journal: Pharmaceutics

Article Title: New Eye Drop Formulation Based on Desonide and Xanthan Gum in Dry Eye Disease: Nonclinical Studies

doi: 10.3390/pharmaceutics17020235

Figure Lengend Snippet: Effect of different concentrations of desonide disodium phosphate (DES) on prostaglandin E2 (PGE 2 ) accumulation in the aqueous humor at 24 h from the intravitreal injection of the lipopolysaccharide (LPS). Data are graphed as floating bars, spanning from minimum to maximum, and as a line at the mean value of measurements in 10 animals per group. ** p < 0.01, One-way ANOVA plus Holm–Sidak post hoc test, DES vs. saline (VHC).

Article Snippet: The prostaglandin E2 (PGE 2 ) enzyme immunoassay (EIA) kit was from Cayman Chemical Company (Ann Arbor, MI, USA).

Techniques: Injection, Saline